Ph.D., Chemistry

Vanderbilt University

Nashville, TN

2022 - 2017

• Dissertation: Improving Untargeted Molecular Annotation Using Structurally-Specific Ion Mobility-Mass Spectrometry
• https://ir.vanderbilt.edu/handle/1803/17403
• John A. McLean Research Group

B.S., Chemistry

Belmont University

Nashville, TN

2017 - 2013

Field Sales Account Manager

Waters Corporation

Nashville, TN

Current - 2022

• Created and executed business plans for a large geographic territory, including sales of analytical instrumentation (LC-MS), managing customer relationships, and coordinating outreach and prospecting events.

Analytical Chemist Summer Intern

Carlisle Construction Materials

Carlisle, PA

2016

• Completed analytical projects relating to production QC and warranty claims. Developed rheological methods and SOPs for new product lines, and trained staff on use and maintenance of the rheometer.

Graduate Research Assistant

McLean Laboratory

Vanderbilt University

2022 - 2017

• Explored strategies for improving compound identifications in untargeted -omics studies using ion mobility-derived collision cross sections (CCS). Developed standardization and reporting recommendations for CCS values in order to build databases and implement algorithms for obtaining high-confidence molecular identifications. Other projects included LC-MS/MS method optimization and data analysis pipeline development for application to various biological systems in collaboration with the Center for Innovative Technology.

Undergraduate Researcher

Spence Laboratory

Belmont University

2017 - 2016

• Alignment and completion of the optical set up of a cavity ring-down spectroscopy instrument.

Undergraduate Researcher

Stace Laboratory

Belmont University

2016 - 2015

• Synthesis and characterization of an enzyme-mimic copper(II) Schiff-base complex. Exploration of the kinetics of its reaction with oxalic acid using spectroscopic methods.

Graduate Teaching Assistant

Vanderbilt Chemistry Department

Nashville, TN

2021 - 2017

• General Chemistry Lab, Analytical Chemistry Lab, and Capstone Advanced Integrated Lab

Structural Characterization of Previously Unresolved Lipids with HRIM-Mass Spectrometry

Rose, B. S., Reardon, A. R., Leaptrot, K. L., May, J. C., McLean, J. A.

N/A

2022

• MOBILion Systems Technical Breakfast Seminar at ASMS. Minneapolis, MN
• Invited oral presentation

Lipid Collision Cross Section Calibration Strategies for High Resolution SLIM-based Traveling Wave Ion Mobility Separations

Rose, B. S., Leaptrot, K. L., Reardon, A. R., May, J. C., McLean, J. A.

N/A

2021

• 69th Annual Conference for the American Society of Mass Spectrometry and Allied Topics. Philadelphia, PA
• Poster presentation

Collision cross section calibration strategies for a prototype SLIM-based ion mobility instrument

Rose, B. S., Leaptrot, K. L., Wormwood, K. L. M., May, J. C., McLean, J. A.

N/A

2020

• Annual Conference for the American Society of Mass Spectrometry and Allied Topics “Reboot”
• Poster presentation

Achieving a Consistent and Unified Community-wide Molecular Database: The Collision Cross Section Compendium

Rose, B. S., Picache, J. A., May, J. C., McLean, J. A.

N/A

2019

• 1st Annual Agilent North American Ion Mobility Workshop. Raleigh, NC.
• Invited oral presentation

Integrated multidimensional liquid chromatography-ion mobility-tandem mass spectrometry (LC-IM-MS/MS) workflow for high-confidence annotations in untargeted lipidomics

Rose, B. S.; Codreanu, S. G., May, J. C., Sherrod, S. D., McLean, J. A.

N/A

2019

• 67th Annual Conference for the American Society of Mass Spectrometry and Allied Topics. Atlanta, GA.
• Oral presentation

Development of a LC-IM-MS/MS workflow for high confidence lipidomics

Rose, B. S.; Codreanu, S. G.; May, J. C., Sherrod, S. D., McLean, J. A

N/A

2018

• Southeastern Lipid Research Conference. Nashville, TN.
• Poster presentation

A Collision Cross Section Calibration Strategy for Lipid Measurements in SLIM-based High Resolution Ion Mobility

Rose, B. S.; May, J. C.; Reardon, A. R.; McLean, J. A.

N/A

2022

• Journal of the American Society for Mass Spectrometry
• Accepted

Improving confidence in lipidomic annotations by incorporating empirical ion mobility regression analysis and chemical class prediction

Rose, B. S.; May, J. C.; Picache, J. A.; Codreanu, S. G.; Sherrod, S. D.; McLean, J. A.

N/A

2022

• Bioinformatics
• DOI: 10.1093/bioinformatics/btac197

High confidence shotgun lipidomics using structurally selective ion mobility-mass spectrometry

Rose, B. S.; Leaptrot, K. L.; Harris, R. A.; Sherrod, S. D.; May, J. C.; McLean, J. A.

N/A

2021

• Shotgun Lipidomics: Methods and Protocols
• DOI: 10.1007/978-1-0716-1410-5_2

Resolving Power and Collision Cross Section Measurement Accuracy of a Prototype High-Resolution Ion Mobility Platform Incorporating Structures for Lossless Ion Manipulation

May, J. C.; Leaptrot, K. L.; Rose, B. S.; Moser, K. L. M.; Deng, L.; Maxon, L.; DeBord, D.; McLean, J. A.

N/A

2021

• Journal of the American Society for Mass Spectrometry
• DOI: 10.1021/jasms.1c00056

Collision cross section compendium to filter and predict multi-omic compound identities.

Picache, J. A.; Rose, B. S.; Balinski, A.; Leaptrot, K. L.; Sherrod, S. D.; May, J. C.; McLean, J. A.

N/A

2019

• Chemical Science
• DOI: 10.1039/c8sc04396e

Untargeted molecular discovery in primary metabolism: collision cross section as a molecular descriptor in ion mobility-mass spectrometry

Nichols, C. M., Dodds, J. N.; Rose, B. S.; Picache, J. A., Morris, C. M.; May, J. C., Sherrod, S. D., McLean, J. A.

N/A

2018

• Analytical Chemistry
• DOI: 10.1021/acs.analchem.8b04322

ASMS Student Travel Award

American Society for Mass Spectrometry

N/A

2020

Student Travel Award

May Institute for Computational Statistics in Mass Spectrometry

N/A

2019

VICB Research Fellowship

Vanderbilt Institute of Chemical Biology

N/A

2018

Mitchum E. Warren Fellowship

Vanderbilt Chemistry Department

N/A

2017